Recombinant Rat CXCL9 (MIG)
CXCL9 (MIG) is a T-cell chemoattractant. Induced by IFN-gamma (IFN-γ), the ELR-negative chemokine CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3. Rat CXCL9 Recombinant Protein is purified CXCL9 (MIG) produced in yeast.
Recombinant Rat CXCL9 (MIG)
Chemokine (C-X-C motif) ligand 9 (CXCL9), also commonly known as monokine induced by interferon-gamma (MIG), is a small cytokine belonging to the CXC chemokine family and is closely related to two other ELR-negative CXC chemokines: CXCL10 and CXCL11.
There have been 17 different C-X-C chemokines described in mammals that are subdivided into two categories: those with a specific amino acid sequence (or motif) of glutamic acid-leucine-arginine (or ELR for short) immediately before the first cysteine of the C-X-C motif (ELR-positive), and those without an ELR motif (ELR-negative). ELR-positive C-X-C chemokines specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. C-X-C chemokines that lack the ELR motif are chemoattractant for lymphocytes.
CXCL9 (MIG) is a T-cell chemoattractant. Induced by IFN-gamma (IFN-γ), the ELR-negative chemokine CXCL9 (MIG) elicits its effects by binding to the cell surface chemokine receptor CXCR3.
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TLVIRNQRCS CISTSQGTFH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSARV KKLMKEWEKK ISQKKKQKRG KNHQRSKKTR KAKTPHHPES KKTA (104)
Yeast
Recombinant proteins produced in yeast
United States
The rat CXCL9/MIG protein can be used in cell culture, as a CXCL9/MIG ELISA Standard, and as a Western Blot Control.