Anti-TRESK K+ Channel Antibody (N467/1)

Name: Anti-TRESK K+ Channel Antibody
Brand: NeuroMab
SKU: 75-475
Price: 319.0 USD
Availability: InStock

Our Anti-TRESK mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N467/1. It detects mouse and rat TRESK, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat brain membrane immunoblot.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-475

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

TRESK

Target Description

Potassium two pore domain channel subfamily K member 18 is encoded by the gene KCNK18. KCNK18 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK18 is an outward rectifying potassium channel that produces rapidly activating outward rectifier K+ currents. KCNK18 is expressed in the brain, spinal cord, and testis. Diseases associated with KCNK18 include Migraine With or Without Aura 13 and Migraine with Aura.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N467/1

Isotype

IgG2b

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcnk18 Tresk-2 Tresk2

Molecular Weight

40-50 kDa

Antigen

Fusion protein amino acids 185-283 (intracellular loop) of mouse TRESK (accession number Q6VV64) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2744558

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

TRESK (Potassium channel subfamily K member 18) (TWIK-related individual potassium channel) (TWIK-related spinal cord potassium channel) (Two-pore-domain potassium channel TRESK) (Kcnk180 (TRIK) (Tresk-2) (Tresk2)

UniProt Details

UniProt (Human): Q7Z418
UniProt (Immunogen Species): Q6VV64

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Anti-TRESK K+ Channel Antibody (N467/1)

SKU: 75-475

Product Details

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