Anti-Shank1 And Shank3 Antibody (N367/51)

Name: Anti-Shank1 And Shank3 Antibody
Brand: NeuroMab
SKU: 75-343
Price: 319.0 USD
Availability: InStock

Our Anti-Shank1 and Shank3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N367/51. It detects mouse and rat Shank1 and Shank3, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with HA-tagged Shank1, Shank2, Shank3 or untagged Kv2.1 plasmid and probed with N367/51 (left) or N23B/49 (right) TC supe.

Adult rat hippocampus immunohistochemistry.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-343

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Shank1 and Shank3

Target Description

Shank proteins act as scaffold proteins anchoring and connecting membrane bound receptors and other proteins to the cytoskeleton in neurons to enable cell signaling.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N367/51

Isotype

IgG2a

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Shank1 Shank3 Prosap2

Molecular Weight

190 kDa

Antigen

Fusion protein amino acids 538-626 (SH3 domain) of rat Shank3 (accession number Q9JLU4) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315919

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Cross-reacts with Shank1Does not cross-react with Shank2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP-interacting protein) (SPANK-1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) (Synamon) SH3 and multiple ankyrin repeat domains protein 3 (Shank3) (Proline-rich synapse-associated protein 2) (ProSAP2) (SPANK-2)

UniProt Details

UniProt (Human): Q9BYB0
UniProt (Immunogen Species): Q9JLU4

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Anti-Shank1 And Shank3 Antibody (N367/51)

SKU: 75-343

Product Details

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