Anti-SUR2A Antibody (N319A/14)

Name: Anti-SUR2A Antibody
Brand: NeuroMab
SKU: 75-296
Price: 319.0 USD
Availability: InStock

Our Anti-SUR2A mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N319A/14. It is KO validated, detects mouse and rat SUR2A, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Immunoblot versus extracts of heart tissue from WT and SUR2 KO mice probed with N319A/14 TC supe. Data courtesy of William Coetzee and Margaret Rice, New York University SOM.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

Go to Full Product Details

Data Sheet

KO Validated

SKU: 75-296

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

SUR2A

Target Description

Sulfonylurea receptor 2A (SUR2A), or ATP binding cassette transporter subfamily C member 9 is encoded by the gene ABCC9 and is a member of the ABC transporter super family. Differential splicing of the ABCC9 gene produces 2 isoforms, SUR2A and SUR2B. SUR2A forms cardiac and smooth muscle-type KATP channels with KCNJ11(Kir6.2) and is involved in regulation and activation. Diseases associated with this gene include Cantu Syndrome and Dilated Cardiomyopathy 1O.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N319A/14

Isotype

IgG2a

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Abcc9 Sur2

Molecular Weight

120 kDa

Antigen

Fusion protein amino acids 1505-1546 (SSIVDAGLVLVFSEGILVECDTGPNLLQHKNGLFSTLVMTNK, cytoplasmic C-terminus) of mouse SUR2A (accession number P70170) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315928

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with SUR2B

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

ATP-binding cassette sub-family C member 9 (Sulfonylurea receptor 2)

UniProt Details

UniProt (Human): O60706
UniProt (Immunogen Species): P70170

Product Specific References for Applications and Species

Immunohistochemistry: Rat
Western Blot: Mouse

Immunohistochemistry: Rat
PMID	Dilution	Publication
23066018	1:50	Hong, M., et al. 2012. Heterogeneity of ATP-sensitive K+ channels in cardiac myocytes: enrichment at the intercalated disk.. Journal of Biological Chemistry, 41258-41267.

Western Blot: Mouse
PMID	Dilution	Publication
23066018	1:300	Hong, M., et al. 2012. Heterogeneity of ATP-sensitive K+ channels in cardiac myocytes: enrichment at the intercalated disk.. Journal of Biological Chemistry, 41258-41267.

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Anti-SUR2A Antibody (N319A/14)

SKU: 75-296

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-SUR2A Antibody

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