Anti-TrpC4 Antibody (N77/15)
Our Anti-TrpC4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N77/15. It detects human, mouse, and rat TrpC4, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with TrpC4 and probed with N77/15 TC supe.
Product Specific References for Applications and Species
- Immunohistochemistry: Rat
- Immunoprecipitation: Mouse
- Western Blot: Guinea Pig | Human | Mouse | Rat
- Additional Publications: Unspecified
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 24782410 | 1:50 | Sung, H.H., et al. 2014. Increased expression of TRPC4 channels associated with erectile dysfunction in diabetes.. Andrology, 550-558. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 24599464 | 5ug | Riccio, A., et al. 2014. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.. Journal of Neuroscience, 3653-3667. |
| Western Blot: Guinea Pig | ||
| PMID | Dilution | Publication |
| 22744007 | not listed | Inoue, M., et al. 2012. Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells.. American Journal of Physiology-Cell Physiology, C635-644. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 25647156 | not listed | Kurahara, L.H., et al. 2015. Intestinal myofibroblast TRPC6 channel may contribute to stenotic fibrosis in Crohn''s disease.. Inflammatory Bowel Diseases, 496-506. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 36257322 | not listed | Kollewe, A., et al. 2022. Subunit Composition, Molecular Environment, and Activation of Native TRPC Channels Encoded by Their Interactomes. Neuron, 4162-4175. |
| 36077460 | not listed | Amores-Bonet, L., et al. 2022. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ into Neurons. International Journal of Molecular Science, 10027. |
| 30038709 | 1:200 | Cheung, S.Y., et al. 2018. TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Oncotarget, 29634-29643. |
| 29273760 | not listed | Soni, H., et al. 2017. Urotensin II-induced store-operated Ca2+ entry contributes to glomerular mesangial cell proliferation and extracellular matrix protein production under high glucose conditions. Scientific Reports, 18049. |
| 24599464 | 5ug/ml | Riccio, A., et al. 2014. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.. Journal of Neuroscience, 3653-3667. |
| 24097979 | 1:2000 | Abou-Saleh, H., et al. 2013. Inositol 1,4,5-trisphosphate (IP3) receptor up-regulation in hypertension is associated with sensitization of Ca2+ release and vascular smooth muscle contractility.. The Journal of Biological Chemistry, 32941-32951. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 24782410 | 1:2000 | Sung, H.H., et al. 2014. Increased expression of TRPC4 channels associated with erectile dysfunction in diabetes.. Andrology, 550-558. |
| 22457348 | not listed | Jeon, J.P., et al. 2012. Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.. The Journal of Biological Chemistry, 17029-17039. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 28455787 | Wang, L.K., et al. 2017. Elevated Expression of TRPC4 in Cortical Lesions of Focal Cortical Dysplasia II and Tuberous Sclerosis Complex. Journal of Molecular Neuroscience, 222-231. | |
| 26988269 | Klipec, W.D., et al. 2016. Loss of the trpc4 gene is associated with a reduction in cocaine self-administration and reduced spontaneous ventral tegmental area dopamine neuronal activity, without deficits in learning for natural rewards. BehaviorBrain Research, 117-127. | |
| 22847694 | Lee, J.E., et al. 2012. Mass spectrometric analysis of novel phosphorylation sites in the TRPC4β channel.. Rapid Communications in Mass Spectrometry, 1965-1970. | |