Anti-TrpC5 Antibody (N67/15)
Our Anti-TrpC5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N67/15. It is KO validated, detects guinea pig, human, mouse, and rat TrpC5, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Adult rat hippocampal immunohistochemistry.
Guinea Pig, Human, Mouse, Rat
ICC, IHC, IP, WB
Mouse
KO Validated
Product Specific References for Applications and Species
- Immunocytochemistry: Guinea Pig | Human | Mouse
- Immunohistochemistry: Guinea Pig | Human | Mouse | Rat
- Immunoprecipitation: Mouse
- Western Blot: Guinea Pig | Mouse | Rat
- Additional Publications: Unspecified
| Immunocytochemistry: Guinea Pig | ||
| PMID | Dilution | Publication |
| 21285322 | 1:500 | Qiu, J., et al. 2011. Guinea pig kisspeptin neurons are depolarized by leptin via activation of TRPC channels.. Endocrinology, 1503-1514. |
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 18832422 | 1:100 | Gomis, A., et al. 2008. Hypoosmotic- and pressure-induced membrane stretch activate TRPC5 channels.. The Journal of Physiology, 5633-5649. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36077460 | not listed | Amores-Bonet, L., et al. 2022. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ …. International Journal of Molecular Science, 10027. |
| 30062674 | not listed | Park, S.E., et al. 2019. Contribution of zinc-dependent delayed calcium influx via TRPC5 in oxidative neuronal death and its prevention by novel TRPC antagonist. Molecular Neurobiology, 2822-2835. |
| 20978238 | 1:50 | Tian, D., et al. 2010. Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels.. Science Signaling, ra77. |
| Immunohistochemistry: Guinea Pig | ||
| PMID | Dilution | Publication |
| 24703699 | 1:500 | Qiu, J., et al. 2014. Insulin excites anorexigenic proopiomelanocortin neurons via activation of canonical transient receptor potential channels.. Cell Metabolism, 682-693. |
| Immunohistochemistry: Human | ||
| PMID | Dilution | Publication |
| 22025699 | 1:200 | Zimmermann, K., et al. 2011. Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system.. PNAS: USA, 18114-18119. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36323817 | 1:500 | Su, C.L., et al. 2022. Wireless neuromodulation in vitro and in vivo by intrinsic TRPC-mediated magnetomechanical stimulation. Communications Biology, 1166. |
| 23188715 | not listed | Phelan, K.D., et al. 2013. Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms.. Molecular Pharmacology, 429-438. |
| 22037305 | 5ug/ml | Gilliam, J.C., et al. 2011. TRP channel gene expression in the mouse retina.. Vision Research, 2440-2452. |
| 19450521 | 1:500 | Riccio, A., et al. 2009. Essential role for TRPC5 in amygdala function and fear-related behavior.. Cell, 761-772. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 35857479 | not listed | Westerling-Bui, A.D., et al. 2022. Transplanted Organoids Empower Human Preclinical Assessment of Drug Candidate for the Clinic. Science Advances, eabj5633. |
| 21179559 | not listed | Cvetkovic-Lopes, V., et al. 2010. Rat hypocretin/orexin neurons are maintained in a depolarized state by TRPC channels.. PLoS One, e15673. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 24599464 | 5ug | Riccio, A., et al. 2014. Decreased anxiety-like behavior and Gαq/11-dependent responses in the amygdala of mice lacking TRPC4 channels.. Journal of Neuroscience, 3653-3667. |
| 19450521 | 5ug | Riccio, A., et al. 2009. Essential role for TRPC5 in amygdala function and fear-related behavior.. Cell, 761-772. |
| Western Blot: Guinea Pig | ||
| PMID | Dilution | Publication |
| 22744007 | not listed | Inoue, M., et al. 2012. Mechanisms and roles of muscarinic activation in guinea-pig adrenal medullary cells.. American Journal of Physiology-Cell Physiology, C635-C644. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 36077460 | not listed | Amores-Bonet, L., et al. 2022. Interactions between the Polysialylated Neural Cell Adhesion Molecule and the Transient Receptor Potential Canonical Channels 1, 4, and 5 Induce Entry of Ca2+ …. International Journal of Molecular Science, 10027. |
| 30062674 | not listed | Park, S.E., et al. 2019. Contribution of zinc-dependent delayed calcium influx via TRPC5 in oxidative neuronal death and its prevention by novel TRPC antagonist. Molecular Neurobiology, 2822-2835. |
| 30038709 | 1:200 | Cheung, S.Y., et al. 2018. TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Oncotarget, 29634-29643. |
| 29920354 | 1:500 | Lee, S.H., et al. 2018. Peripheral serotonin receptor 2B and transient receptor potential channel 4 mediate pruritus to serotonergic antidepressants in mice. Journal of Allergy and Clinical Immunology, 1349-1352. |
| 26133660 | not listed | Hong, C., et al. 2015. Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington''s disease.. Brain, 3030-3047. |
| 23858470 | 1:1000 | Park, S.H., et al. 2013. Leptin promotes K(ATP) channel trafficking by AMPK signaling in pancreatic β-cells.. PNAS: USA, 12673-12678. |
| 22547824 | 1:500 | Kaczmarek, J.S., et al. 2012. Calpain cleaves and activates the TRPC5 channel to participate in semaphorin 3A-induced neuronal growth cone collapse.. PNAS: USA, 7888-7892. |
| 22037305 | 2ug/ml | Gilliam, J.C., et al. 2011. TRP channel gene expression in the mouse retina.. Vision Research, 2440-2452. |
| 22031853 | not listed | Kim, E.Y., et al. 2011. Insulin increases surface expression of TRPC6 channels in podocytes: role of NADPH oxidases and reactive oxygen species.. American Journal of Physiology-Renal Physiology, F298-F307. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 38537434 | 1:200 | Luo, R, et al. 2024. STIM2 variants regulate Orai1/TRPC1/TRPC4-mediated store-operated Ca2+ entry and mitochondrial Ca2+ homeostasis in cardiomyocytes. Cell Calcium, 102871. |
| 35805070 | 1:1000 | Kim, E.Y., et al. 2022. TRPC6 Inactivation Reduces Albuminuria Induced by Protein Overload in Sprague Dawley Rats. Cells, 1985. |
| 32123821 | 1:200 | Hassanzadeh Khayyat, N., et al. 2019. TRPC6 inactivation does not protect against diabetic kidney disease in streptozotocin (STZ)‐treated Sprague‐Dawley rats. FASEB Bioadvances, 773-782. |
| 22457348 | not listed | Jeon, J.P., et al. 2012. A novel direct activation mechanism of TRPC4 and TRPC5 channels by selective Gαi subunits. Journal of Biological Chemistry, 17029-17039. |
| 22457348 | not listed | Jeon, J.P., et al. 2012. Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.. The Journal of Biological Chemistry, 17029-17039. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 20426773 | Salomonsson, M., et al. 2010. Na+-independent, nifedipine-resistant rat afferent arteriolar Ca2+ responses to noradrenaline: possible role of TRPC channels.. Acta Physiologica, 265-278. | |