Anti-GABA-A-R, Delta Antibody (N151/3)

4 Citations

Our Anti-GABA(A)R, Delta mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N151/3. It detects mouse and rat GABA(A)R, Delta, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Cerebellar lysate immunoblot probed with N151/3 (3 mg/mL).
Cerebellar lysate immunoblot probed with N151/3 (3 mg/mL).
Roll over image to zoom in Click on image to zoom
Cerebellar lysate immunoblot probed with N151/3 (3 mg/mL).
Cultured rat hippocampal neuron surface (S, left) and total (T, right) protein immunofluorescence staining (green) with N151/3 (2 mg/mL).
Hippocampus immunohistochemistry with N151/3 (5 mg/mL).

Mouse, Rat
ICC, WB
Mouse
490
550
594
650
Carrier-Free

Go to Full Product Details

Data Sheet

SKU: 75-171

Volume: 100 µL
Price:
$329.00
Ships: 1-2 business days

Product Details

GABA(A)R, Delta
Gamma-aminobutyric acid receptor subunit delta or Delta GABA-A receptor is encoded by the gene GABRD. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR delta is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR delta is highly expressed in brain at the cell junction, synapse, postsynaptic cell membrane and cytoplasmic vesicle membrane. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N151/3
IgG2a
ICC, WB
Mouse
Gabrd
55 kDa
Synthetic peptide amino acids 15-34 (CTQPHHGARAMNDIGDYVGS, extracellular N-terminus) of rat GABA-A-R-Delta (accession number P18506)
Mouse, Rat
AB_2107254
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.99
Unconjugated
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta)
P18506

Product Specific References for Applications and Species

Immunocytochemistry: Rat
PMID Dilution Publication
2371457620ug/mlJoshi, S., et al. 2013. GABAA receptor membrane insertion rates are specified by their subunit composition.. Molecular and Cellular Neuroscience, 201-211.
Western Blot: Human
PMID Dilution Publication
386239671:1000Bundy, J., et al. 2024. Role of β3 subunit of the GABA type A receptor in triple negative breast cancer proliferation, migration, and cell cycle progression. Cell Cycle, 448-465.
Western Blot: Rat
PMID Dilution Publication
235850585ug/mlJoshi, S., et al. 2013. N-methyl-D-aspartic acid receptor activation downregulates expression of δ subunit-containing GABAA receptors in cultured hippocampal neurons.. Molecular Pharmacology, 1-11.
Additional Publications: Unspecified
PMID Publication
21439793Kharlamov, E.A., et al. 2011. Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy.. Epilepsy Research, 20-34.

Bulk Order Anti-GABA-A-R, Delta Antibody

Related Products

Recently Viewed