Anti-Nav1.4 Sodium Channel Antibody FL490 Conjugate (N255/38)

Name: Anti-Nav1.4 Sodium Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-424-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Nav1.4 sodium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N255/38. It detects rat Nav1.4 sodium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-424-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Nav1.4 sodium channel

Target Description

Sodium channel subunit beta-1or Navbeta1 Na+ channel is encoded by SCN1B. Voltage gated sodium channels are made up of an alpha (pore forming) subunit and 1 or 2 beta subunits. SCN1B has two splice variants. Navß1 is a transmembrane protein and acts as a regulatory subunit in excitable membranes and modulates the kinetics of channel inactivation. It is found expressed in brain, spinal cord, heart and skeletal muscle. Diseases associated with SCN1B include several types of epilepsy.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N255/38

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Scn4a

Molecular Weight

>200 kDa

Antigen

Fusion protein amino acids 269-386 (Repeat I external pore between S5 and S6) of rat Nav1.4 (accession number P15390) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940408

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Sodium channel protein type 4 subunit alpha (Mu-1) (SkM1) (Sodium channel protein skeletal muscle subunit alpha) (Sodium channel protein type IV subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.4)

UniProt Details

UniProt (Human): P35499
UniProt (Immunogen Species): P15390

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Anti-Nav1.4 Sodium Channel Antibody FL490 Conjugate (N255/38)

SKU: 75-424-FL490

Product Details

Bulk Order Anti-Nav1.4 Sodium Channel Antibody FL490 Conjugate

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