Anti-SynCAM4 Antibody FL650 Conjugate (N244/5)

Name: Anti-SynCAM4 Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-247-FL650
Price: 460.0 USD
Availability: InStock

Our Anti-SynCAM4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N244/5. It is KO validated, detects human, mouse, and rat SynCAM4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

550

594

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Data Sheet

KO Validated

SKU: 75-247-FL650

Product Details

Target

SynCAM4

Target Description

SynCAM4 cell adhesion molecule, Immunoglobulin Superfamily, Member 4C (IGSF4C), or Nectin-Like Protein 4 (NECL4) is encoded by the gene CADM4 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam4 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in several tissue types including brain, kidney and liver. Diseases associated with with this gene include Small Intestine Adenocarcinoma.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N244/5

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Cadm4 Igsf4c Necl4 Tsll2

Molecular Weight

43 kDa

Antigen

Fusion protein amino acids 1-321 (signal peptide and extracellular N-terminus) of mouse SynCAM4 (accession number Q8R464) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939903

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with other SynCAMs (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Cell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)

UniProt Details

UniProt (Human): Q8NFZ8
UniProt (Immunogen Species): Q8R464

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Anti-SynCAM4 Antibody FL650 Conjugate (N244/5)

SKU: 75-247-FL650

Product Details

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