Anti-Kv1.5 K+ Channel Antibody (K7/45)
Our Anti-Kv1.5 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K7/45. It detects human, mouse, and rat Kv1.5 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Immunoblot on adult rat brain membrane (RBM) and lysates from Kv1.5-transfected (COS+) and untransfected (COS-) COS cells.
Product Specific References for Applications and Species
- Immunocytochemistry: Mouse | Rat
- Immunohistochemistry: Mouse | Rat
- Immunoprecipitation: Human
- PLA: Mouse
- Water Blot: Mouse
- Western Blot: Human | Mouse | Rat
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 38978788 | 1:50 | Raph, S, et al. 2024. Kv beta complex facilitates exercise-induced augmentation of myocardial perfusion and cardiac growth. Frontiers in Cardiovascular Medicine, 1411354. |
| 35440632 | 1:50 | Dwenger, M.M., et al. 2022. Pyridine Nucleotide Redox Potential in Coronary Smooth Muscle Couples Myocardial Blood Flow to Cardiac Metabolism. Nature Communications, 2051. |
| 31639389 | not listed | Kilfoil, P.J., et al. 2019. Metabolic regulation of Kv channels and cardiac repolarization by Kvβ2 subunits. Journal of molecular and cell cardiology, 93–106. |
| 28342889 | 1:40 | Nystoriak, M.A., et al. 2017. Heteromeric complexes of aldo-keto reductase auxiliary KVβ subunits (AKR6A) regulate sarcolemmal localization of KV1. 5 in coronary arterial myocytes. . Chemico-biological interactions, 210-217. |
| 21233214 | 1:1000 | Fulton, S., et al. 2011. Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow.. The Journal of Biological Chemistry, 9360-9372. |
| 20299686 | 1:50 | Cidad, P., et al. 2010. Characterization of ion channels involved in the proliferative response of femoral artery smooth muscle cells.. Arterioscler Thromb Vasc Biol., 1203-1211. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 27958660 | 1:100 | Kidd, M.W., et al. 2017. Angiotensin II reduces the surface abundance of KV1. 5 channels in arterial myocytes to stimulate vasoconstriction. . The Journal of Physiology, 1607-1618. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36640913 | 1:500 | Otuyemi, B., et al. 2023. Domain and Cell Type-specific Immunolocalisation of Voltage-gated Potassium Channels in the Mouse Striatum. Journal of Chemical Neuroanatomy, 102233. |
| 28715117 | 1:5000 | Ohgomori, T., et al. 2017. Differential activation of neuronal and glial STAT 3 in the spinal cord of the SOD 1G93A mouse model of amyotrophic lateral sclerosis.. European Journal of Neuroscience, 2001-2014. |
| 22987820 | 1:5000 | Yamada, J., et al. 2013. Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis.. Journal of Comparative Neurology, 1184-1201. |
| 20299686 | not listed | Cidad, P., et al. 2010. Characterization of ion channels involved in the proliferative response of femoral artery smooth muscle cells.. Arterioscler Thromb Vasc Biol., 1203-1211. |
| 19091962 | 1:1000 | Miller, M.N., et al. 2008. Region-specific spike-frequency acceleration in layer 5 pyramidal neurons mediated by Kv1 subunits.. Journal of Neuroscience, 13716-13726. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 23318870 | not listed | Ovsepian, S.V., et al. 2013. A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets.. The Journal of Physiology, 1771-91. |
| Immunoprecipitation: Human | ||
| PMID | Dilution | Publication |
| 28072464 | 2 μg | Xiao, G.S., et al. 2017. Genistein and tyrphostin AG556 decrease ultra‐rapidly activating delayed rectifier K+ current of human atria by inhibiting EGF receptor tyrosine kinase. . British Journal of Pharmacology, 454-467. |
| PLA: Mouse | ||
| PMID | Dilution | Publication |
| 31639389 | not listed | Kilfoil, P.J., et al. 2019. Metabolic regulation of Kv channels and cardiac repolarization by Kvβ2 subunits.. Journal of Molecular and Cellular Cardiology, 93-106. |
| Water Blot: Mouse | ||
| PMID | Dilution | Publication |
| 25670860 | 1:2 (supe) | Nieves-Cintrón, M., et al. 2015. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes.. The Journal of Biological Chemistry, 7918-29. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 20533281 | not listed | Stockwin, L.H., et al. 2010. Sodium dichloroacetate selectively targets cells with defects in the mitochondrial ETC.. International Journal of Cancer, 2510-2519. |
| 18570888 | not listed | Nanduri, J., et al. 2008. Mitochondrial reactive oxygen species mediate hypoxic down-regulation of hERG channel protein.. Biochemical and Biophysical Research Communications, 309-314. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 37336943 | 1:1000 | Al-Owais, MM, et al. 2023. Inhibition of the Voltage-gated Potassium Channel Kv1.5 by Hydrogen Sulfide Attenuates Remodeling Through S-nitrosylation-mediated Signaling. Communications Biology, 651. |
| 36842733 | not listed | Markandeya, Y.S., et al. 2023. Caveolin-3 and Caveolae Regulate Ventricular Repolarization. Journal of Molecular and Cellular Cardiology, 38-49. |
| 31028120 | not listed | Dong, X., et al. 2019. Dlg1 maintains dendritic cell function by securing voltage-gated K+ channel integrity. . The Journal of Immunology, 3187-3197. |
| 26205295 | 1:500 | El Gebeily, G., et al. 2015. Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart.. Journal of Molecular and Cellular Cardiology, 85-94. |
| 25447080 | 1:300 | Gillet, L., et al. 2015. Cardiac-specific ablation of synapse-associated protein SAP97 in mice decreases potassium currents but not sodium current. Heart Rhythm, 181-192. |
| 24723263 | 1:100 | Dufour, M.A., et al. 2014. Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development.. Journal of Neuroscience Research, 981-99. |
| 24494598 | not listed | Speca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408. |
| 24375641 | 1:200 | Lopez-Izquierdo, A., et al. 2014. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.. American Journal of Physiology-Heart and Circulatory Physiology, H747-H754. |
| 16943244 | not listed | Pott, C., et al. 2007. Mechanism of shortened action potential duration in Na+-Ca2+ exchanger knockout mice.. American Journal of Physiology-Cell Physiology, C968-73. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 27958660 | 1:1000 | Kidd, M.W., et al. 2017. Angiotensin II reduces the surface abundance of KV1. 5 channels in arterial myocytes to stimulate vasoconstriction. . The Journal of Physiology, 1607-1618. |
| 19411284 | not listed | Tobin, A.A., et al. 2009. Loss of cerebrovascular Shaker-type K(+) channels: a shared vasodilator defect of genetic and renal hypertensive rats.. American Journal of Physiology-Heart and Circulatory Physiology, H293-H303. |