Anti-Mortalin/GRP75 Antibody (N52A/42)

Our Anti-Mortalin/GRP75 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N52A/42. It detects human, mouse, and rat Mortalin/GRP75, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.



SKU: 75-127

Volume: 100 µL
1-2 business days
Price:
Sale price$374.00

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
324323791:1000Acin‐Perez, R., et al. 2020. A novel approach to measure mitochondrial respiration in frozen biological samples. The EMBO Journal, e104073.
28057766not listedSteffen, J., et al. 2017. Rapid degradation of mutant SLC25A46 by the ubiquitin-proteasome system results in MFN1/2-mediated hyperfusion of mitochondria. Molecular and Cellular Biology, 600-612.
Immunocytochemistry: Mouse
PMID Dilution Publication
377225691:50Bueno, D, et al. 2023. NECAB2 is an endosomal protein important for striatal function. Free Radical Biology & Medicine, 643-656.
32235845not listedZieger, H.L., et al. 2020. Disease-associated synaptic scaffold protein CNK2 modulates PSD size and influences localisation of the regulatory kinase TNIK. Scientific Reports, 5709.
305906151:200Dong, Y.N., et al. 2019. GRP75 overexpression rescues frataxin deficiency and mitochondrial phenotypes in Friedreich ataxia cellular models. . Human molecular genetics, 1594-1607.
Western Blot: Human
PMID Dilution Publication
356622771:1000Wolf, C., et al. 2022. GDAP1 loss of function inhibits the mitochondrial pyruvate dehydrogenase complex by altering the actin cytoskeleton. Communications Biology, 541.
33730581not listedAcoba, M.G., et al. 2021. The mitochondrial carrier SFXN1 is critical for complex III integrity and cellular metabolism. Cell Reports, 108869.
313253441:5000Jurek, B., et al. 2019. Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function. Annals of Neurology, 656-670.
292535891:1000Blunsom, N.J., et al. 2018. Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1. Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, 284-298.
28404750not listedLu, Y.W., et al. 2017. Human adenine nucleotide translocases physically and functionally interact with respirasomes. Molecular and Cellular Biology, 1489-1506.
27616904not listedHwang, J.Y., et al. 2016. Proteomic analysis reveals that the protective effects of ginsenoside Rb1 are associated with the actin cytoskeleton in β-amyloid-treated neuronal cells. Journal of Ginseng Research, 278-284.
27543974not listedWan, J., et al. 2016. Loss of function of SLC25A46 causes lethal congenital pontocerebellar hypoplasia. Brain, 2877-2890.
26644354not listedGong, B., et al. 2016. Developing high-quality mouse monoclonal antibodies for neuroscience research - approaches, perspectives and opportunities. New Biotechnology, 551-564.
26110647not listedCáceres, M., et al. 2015. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility.. PLoS One, e0130540.
25231975not listedCerda, O., et al. 2015. Casein kinase-mediated phosphorylation of serine 839 is necessary for basolateral localization of the Ca²⁺-activated non-selective cation channel TRPM4.. Pflügers Archiv, 1723-1732.
250273201 : 1000Ramirez, A., et al. 2014. SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer''s disease.. Human Molecular Genetics, 6644-6658.
24001768not listedRunne, C., et al. 2013. PLEKHG2 promotes heterotrimeric G protein βγ-stimulated lymphocyte migration via Rac and Cdc42 activation and actin polymerization.. Molecular and Cellular Biology, 4294-4307.
23269666not listedArango, N.A., et al. 2013. Meiosis I arrest abnormalities lead to severe oligozoospermia in meiosis 1 arresting protein (M1ap)-deficient mice.. Biology of Reproduction, 76.
21712386not listedCerda, O., et al. 2011. Activity-dependent phosphorylation of neuronal Kv2.1 potassium channels by CDK5.. The Journal of Biological Chemistry, 28738-28748.
Western Blot: Mouse
PMID Dilution Publication
384850941ug/mlKang, SK, et al. 2024. Altered neurological and neurobehavioral phenotypes in a mouse model of the recurrent KCNB1-p.R306C voltage-sensor variant. Neurobiology of Disease, 106470.
35943566not listedvan der Kooij, M.A., et al. 2022. Chronic Social Stress Disrupts the Intracellular Redistribution of Brain Hexokinase 3 Induced by Shifts in Peripheral Glucose Levels. Journal of Molecular Medicine, 1441-1453.
354179221:1000Echevarria-Cooper, D.M., et al. 2022. Cellular and behavioral effects of altered NaV1.2 sodium channel ion permeability in Scn2aK1422E mice. Human molecular genetics, 2964-2988.
348228171ug/mlAnderson, L.L., et al. 2022. The endocannabinoid system impacts seizures in a mouse model of Dravet syndrome. Neuropharmacology, 108897.
340860811 ug/mLHawkins, N.A., et al. 2021. Gabra2 is a genetic modifier of Dravet syndrome in mice. Mammalian Genome, 350-363.
335024421:10 (supe)Fortenbach, C., et al. 2021. Loss of the K+ channel Kv2.1 greatly reduces outward dark current and causes ionic dysregulation and degeneration in rod photoreceptors. Journal of General Physiology, .
33436529not listedWang, Y.Q., et al. 2021. AMPA and NMDA Receptor Trafficking at Cocaine-Generated Synapses. Journal of Neuroscience, 1996-2011.
331322031 ug/mLHawkins, N.A., et al. 2021. Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant. Neurobiology of Disease, 105141.
303471901:1000Hawkins, N.A., et al. 2019. Gene expression profiling in a mouse model of Dravet syndrome. Experimental Neurology, 247-256.
30586380not listedFavaro, P.D., et al. 2018. An opposing function of paralogs in balancing developmental synapse maturation. Plos Biology, e2006838.
299766271:1000Shepherd, A.J., et al. 2018. Angiotensin II Triggers Peripheral Macrophage-to-Sensory Neuron Redox Crosstalk to Elicit Pain. Journal of Neuroscience, 7032-7057.
29403353not listedBishop HI, et al. 2018. Kv2 Ion Channels Determine the Expression and Localization of the Associated AMIGO-1 Cell Adhesion Molecule in Adult Brain Neurons.. Frontiers in Molecular Neuroscience, 1.
284907511:1000Anderson, L.L., et al. 2017. Unexpected Efficacy of a Novel Sodium Channel Modulator in Dravet Syndrome. Scientific Reports, 1682.
28344592not listedLarimore, J., et al. 2017. Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus.. Frontiers in Genetics, 28.
280774871:1000Shukla, A., et al. 2017. Calcium‐permeable AMPA receptors and silent synapses in cocaine‐conditioned place preference. The EMBO journal, 36(4), pp.458-474.. The EMBO journal, 458-474.
277686961:1000Hawkins, N.A., et al. 2016. Fine Mapping of a Dravet Syndrome Modifier Locus on Mouse Chromosome 5 and Candidate Gene Analysis by RNA-Seq. PLOS Genetics, e1006398.
271476581:2000Shutov, L.P., et al. 2016. The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1. Journal of Neuroscience, 5055-5070.
271476581:2000Shutov, L.P., et al. 2016. The Complement System Component C5a Produces Thermal Hyperalgesia via Macrophage-to-Nociceptor Signaling That Requires NGF and TRPV1. Journal of Neuroscience, 5055-5070.
26644354not listedGong, B., et al. 2016. Developing high-quality mouse monoclonal antibodies for neuroscience research - approaches, perspectives and opportunities. New Biotechnology, 551-564.
265386601 : 20Bishop, H.I., et al. 2015. Distinct Cell- and Layer-Specific Expression Patterns and Independent Regulation of Kv2 Channel Subtypes in Cortical Pyramidal Neurons.. Journal of Neuroscience, 14922-14942.
26442584not listedCobb, M.M., et al. 2015. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.. The Journal of Biological Chemistry, 29189-29201.
247955611:1000Joaquin N. Lugo, et al. 2014. Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins.. Frontiers in Molecular Neuroscience, 27.
24494598not listedSpeca, D.J., et al. 2014. Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability.. Genes, Brain and Behavior, 394-408.
24068818not listedKrüger, J.M., et al. 2013. Differential roles of postsynaptic density-93 isoforms in regulating synaptic transmission.. Journal of Neuroscience, 15504-15517.
23946397not listedBonnet, S.A., et al. 2013. Synaptic state-dependent functional interplay between postsynaptic density-95 and synapse-associated protein 102.. Journal of Neuroscience, 13398-13409.
23223301not listedKummer M.P., et al. 2012. Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing.. Journal of Neuroscience, 17824-17829.
23012412not listedWinters, B.D., et al. 2012. Cannabinoid receptor 1-expressing neurons in the nucleus accumbens. PNAS USA, E2717-E2725.
229337801:1000Loo, L., et al. 2012. The C-type natriuretic peptide induces thermal hyperalgesia through a noncanonical Gβγ-dependent modulation of TRPV1 channel.. Journal of Neuroscience, 11942-11955.
206919041:1000Wang, G., et al. 2010. PNPASE regulates RNA import into mitochondria.. Cell, 456-467.
Western Blot: Non-human Primate
PMID Dilution Publication
26503721not listedThiffault, I., et al. 2015. A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.. The Journal of General Physiology, 399-410.
Western Blot: Rat
PMID Dilution Publication
26442584not listedCobb, M.M., et al. 2015. Cell Cycle-dependent Changes in Localization and Phosphorylation of the Plasma Membrane Kv2.1 K+ Channel Impact Endoplasmic Reticulum Membrane Contact Sites in COS-1 Cells.. The Journal of Biological Chemistry, 29189-201.
229772511:2000Ulrich, J.D., et al. 2012. Distinct activation properties of the nuclear factor of activated T-cells (NFAT) isoforms NFATc3 and NFATc4 in neurons.. The Journal of Biological Chemistry, 37594-609.
Western Blot: Worm
PMID Dilution Publication
258981131:20 (supe)Lawrence, K.S., et al. 2015. DNA damage response and spindle assembly checkpoint function throughout the cell cycle to ensure genomic integrity.. PLOS Genetics, e1005150.
Additional Publications: Unspecified
PMID Publication
28322444Vicente, P.C., et al. 2018. Identification and characterization of site-specific N-glycosylation in the potassium channel Kv3.1b. Journal of Cell Physiology, 549-558.

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