Anti-SAP102 Antibody (N19/2)
Our Anti-SAP102 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N19/2. It is KO validated, detects human, mouse, and rat SAP102, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Adult rat hippocampus immunohistochemistry.
Human, Mouse, Rabbit, Rat
ICC, IHC, IP, WB
Mouse
KO Validated
Product Specific References for Applications and Species
- Immunocytochemistry: Mouse | Rat
- Immunohistochemistry: Mouse | Rabbit | Rat
- Immuno-Gold labeling: Rat
- Immunoprecipitation: Mouse
- Western Blot: Human | Mouse | Rat
- Additional Publications: Unspecified
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 29415226 | not listed | Mohan, V., et al. 2019. Temporal regulation of dendritic spines through NrCAM-Semaphorin3F receptor signaling in developing cortical pyramidal neurons. Cerebral Cortex, 963-977. |
| 22246437 | 1:1000 | Zheng, S., et al. 2012. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nature Neuroscience, 381-388. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 38582451 | 1:1000-1:5000 | Kunde, SA, et al. 2024. JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines. The Journal of Biological Chemistry, 107263. |
| 26665164 | 1:50 | Tao-Cheng, J.H., et al. 2015. Depolarization of Hippocampal Neurons Induces Formation of Nonsynaptic NMDA Receptor Islands Resembling Nascent Postsynaptic Densities.. eNeuro, . |
| 23904596 | not listed | Oku, Y., et al. 2013. AGAP3 and Arf6 regulate trafficking of AMPA receptors and synaptic plasticity.. Journal of Neuroscience, 12586-12598. |
| 21543610 | 1:500 | Sun, Q., et al. 2011. PSD-95 and PSD-93 play critical but distinct roles in synaptic scaling up and down.. Journal of Neuroscience, 6800-6808. |
| 21048125 | not listed | Steinmetz, C.C., et al. 2010. Tumor necrosis factor-α signaling maintains the ability of cortical synapses to express synaptic scaling.. Journal of Neuroscience, 14685-14690. |
| 20096331 | not listed | Petralia, R.S., et al. 2010. Organization of NMDA receptors at extrasynaptic locations.. Neuroscience, 68-87. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 38837880 | 1:1000 | Hanes, CM, et al. 2024. A C-terminal motif containing a PKC phosphorylation site regulates γ-Protocadherin-mediated dendrite arborization in the cerebral cortex in vivo. Developmental Neurobiology, 217-235. |
| 30078578 | 1:250 | Zhu, F., et al. 2018. Architecture of the mouse brain synaptome. Neuron, 781-799. |
| 25429150 | 1:500 | Williams, L.E., et al. 2014. Regulation of hippocampal synaptic strength by glial xCT.. Journal of Neuroscience, 16093-16102. |
| 25352748 | 1:200 | de Andrade, G.B., et al. 2014. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.. Molecular Vision, 1422-33. |
| 22745750 | 1:100 | Lauks, J., et al. 2012. Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.. PLoS One, e39420. |
| 21940442 | 1:500 | Mondin, M., et al. 2011. Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds.. Journal of Neuroscience, 13500-13515. |
| Immunohistochemistry: Rabbit | ||
| PMID | Dilution | Publication |
| 27558197 | 1:500 | Vila, A., et al. 2017. Membrane‐associated guanylate kinase scaffolds organize a horizontal cell synaptic complex restricted to invaginating contacts with photoreceptors. Journal of Comparative Neurology, 850-867. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 20096331 | not listed | Petralia, R.S., et al. 2010. Organization of NMDA receptors at extrasynaptic locations.. Neuroscience, 68-87. |
| ImmunoGold Labeling: Rat | ||
| PMID | Dilution | Publication |
| 29134655 | 1:20 | Suzuki, T., et al. 2018. Protein components of post‐synaptic density lattice, a backbone structure for type I excitatory synapses. Journal of Neurochemistry, 390-407. |
| 26215919 | 1:10 | Farley, M.M., et al. 2015. Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities.. Neuroscience, 286-301. |
| Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 19726651 | 1ug/ml | Fan, J., et al. 2009. Interaction of postsynaptic density protein-95 with NMDA receptors influences excitotoxicity in the yeast artificial chromosome mouse model of Huntington''s disease.. Journal of Neuroscience, 10928-10938. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 39370692 | not listed | Won, S, et al. 2024. Biochemical Properties of Synaptic Proteins Are Dependent on Tissue Preparation: NMDA Receptor Solubility Is Regulated by the C-Terminal Tail. Journal of Cellular Biochemistry, e30664. |
| 38582451 | 1:1000-1:5000 | Kunde, SA, et al. 2024. JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines. The Journal of Biological Chemistry, 107263. |
| 26595655 | not listed | Jang, S., et al. 2016. Synaptic adhesion molecule IgSF11 regulates synaptic transmission and plasticity. Nature Neuroscience, 84-93. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 39370692 | not listed | Won, S, et al. 2024. Biochemical Properties of Synaptic Proteins Are Dependent on Tissue Preparation: NMDA Receptor Solubility Is Regulated by the C-Terminal Tail. Journal of Cellular Biochemistry, e30664. |
| 36429074 | 1:500 | Flores-Muñoz, C., et al. 2022. The Long-Term Pannexin 1 Ablation Produces Structural And Functional Modifications In Hippocampal Neurons. Cells, 3646. |
| 34613779 | not listed | Ban, Y., et al. 2021. Prickle promotes the formation and maintenance of glutamatergic synapses by stabilizing the intercellular planar cell polarity complex. Science Advances, . |
| 33125726 | not listed | Briševac, D., et al. 2021. The small GTPase Arf6 is dysregulated in a mouse model for fragile X syndrome. Journal of Neurochemistry, 666-683. |
| 33229412 | not listed | Pandian, S., et al. 2020. Myosin va brain-specific mutation alters mouse behavior and disrupts hippocampal synapses. eNeuro, . |
| 33198813 | not listed | Arsenault, D., et al. 2020. Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice. Biology of Sex Difference, 63. |
| 31849613 | not listed | Gutierrez, D.A., et al. 2019. c-Abl Deficiency Provides Synaptic Resiliency Against Aβ-Oligomers. Frontiers in Cellular Neuroscience, 526. |
| 30946007 | 1:2000 | Koster, K.P., et al. 2019. Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model. Elife, e40316. |
| 30936304 | not listed | Won, S., et al. 2019. The STEP61 interactome reveals subunit-specific AMPA receptor binding and synaptic regulation. PNAS, 8028-8037. |
| 30451289 | not listed | Vaden, J.H., et al. 2019. Chronic over-expression of ubiquitin impairs learning, reduces synaptic plasticity, and enhances GRIA receptor turnover in mice. Journal of Neurochemistry, 386-399. |
| 29415226 | not listed | Mohan, V., et al. 2019. Temporal regulation of dendritic spines through NrCAM-Semaphorin3F receptor signaling in developing cortical pyramidal neurons. Cerebral Cortex, 963-977. |
| 30586380 | not listed | Favaro, P.D., et al. 2018. An opposing function of paralogs in balancing developmental synapse maturation. Plos Biology, e2006838. |
| 30078578 | 1:1000 | Zhu, F., et al. 2018. Architecture of the mouse brain synaptome. Neuron, 781-799. |
| 29995933 | not listed | Gupta, P., et al. 2018. SAP97 regulates behavior and expression of schizophrenia risk enriched gene sets in mouse hippocampus. PLoS One, e0200477. |
| 29429936 | not listed | Matt, L., et al. 2018. α-actinin anchors PSD-95 at postsynaptic sites. Neuron, 1094-1109. |
| 28904854 | 1:2000 | Kunde, S.A., et al. 2017. Protein kinase C regulates AMPA receptor auxiliary protein Shisa9/CKAMP 44 through interactions with neuronal scaffold PICK 1. FEBS Open Bio, 1234-1245. |
| 28077487 | 1:1000 | Shukla, A., et al. 2017. Calcium‐permeable AMPA receptors and silent synapses in cocaine‐conditioned place preference.. The EMBO journal, 458-474. |
| 27457929 | not listed | Won, S., et al. 2016. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.. PNAS: USA, E4736-E4744. |
| 27134685 | 1:2000 | Sinclair, D., et al. 2016. Effects of sex and DTNBP1 (dysbindin) null gene mutation on the developmental GluN2B-GluN2A switch in the mouse cortex and hippocampus. Journal of Neurodevelopmental Disorders, 14. |
| 25934101 | 1 : 100 | Farzana, F., et al. 2016. Neurobeachin Regulates Glutamate- and GABA-Receptor Targeting to Synapses via Distinct Pathways.. Molecular Neurobiology, 2112-2123. |
| 29124216 | 1:2000 | Rizzi, S., et al. 2015. Identification of potential novel interaction partners of the sodium-activated potassium channels Slick and Slack in mouse brain. Biochemistry and Biophysics Reports, 291-298. |
| 26005851 | 1:1000 | Shin, S., et al. 2015. mGluR5 in the nucleus accumbens is critical for promoting resilience to chronic stress. Nature Neuroscience, 1017-1024. |
| 25505322 | not listed | Fortin, D.A., et al. 2015. Live imaging of endogenous PSD-95 using ENABLED: a conditional strategy to fluorescently label endogenous proteins.. Journal of Neuroscience, 16698-16712. |
| 24795561 | 1:1000 | Lugo, J.N., et al. 2014. Deletion of PTEN produces autism-like behavioral deficits and alterations in synaptic proteins.. Frontiers in Molecular Neuroscience, 27. |
| 23946397 | not listed | Bonnet, S.A., et al. 2013. Synaptic state-dependent functional interplay between postsynaptic density-95 and synapse-associated protein 102.. Journal of Neuroscience, 13398-13409. |
| 23719805 | 1 : 1000 | Hoy, J.L., et al. 2013. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions.. Journal of Neuroscience, 9364-9384. |
| 22745750 | 1:1000 | Lauks, J., et al. 2012. Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin.. PLoS One, e39420. |
| 22369234 | 1:1000 | Wilke, S.A., et al. 2012. NeuroD2 regulates the development of hippocampal mossy fiber synapses.. Neural Development, 9. |
| 22246437 | 1:1000 | Zheng, S., et al. 2012. PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nature Neuroscience, 381-388. |
| 21808020 | not listed | Etherton, M., et al. 2011. Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function.. PNAS: USA, 13764-13769. |
| 19679819 | not listed | Chaudhury, A., et al. 2009. Role of PSD95 in membrane association and catalytic activity of nNOSalpha in nitrergic varicosities in mice gut.. The American Journal of Gastrointestinal and Liver Physiology, G806-13. |
| 19406213 | not listed | Garside, M.L., et al. 2009. Molecular interactions of the plasma membrane calcium ATPase 2 at pre- and post-synaptic sites in rat cerebellum.. Neuroscience, 383-395. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 38582451 | 1:1000-1:5000 | Kunde, SA, et al. 2024. JNK activity modulates postsynaptic scaffold protein SAP102 and kainate receptor dynamics in dendritic spines. The Journal of Biological Chemistry, 107263. |
| 30067114 | not listed | Liu, M., et al. 2018. SAP102 regulates synaptic AMPAR function through a CNIH-2-dependent mechanism. Journal of Neurophysiology, 1578-1586. |
| 28283559 | not listed | Liu, S., et al. 2017. A rare variant identified within the GluN2B C-terminus in a patient with autism affects NMDA receptor surface expression and spine density. . Journal of Neuroscience, 4093-4102. |
| 27457929 | not listed | Won, S., et al. 2016. PSD-95 stabilizes NMDA receptors by inducing the degradation of STEP61.. PNAS: USA, E4736-E4744. |
| 26247861 | 2ug/ml | Levy, J.M., et al. 2015. Synaptic Consolidation Normalizes AMPAR Quantal Size following MAGUK Loss.. Neuron, 534-548. |
| 24780380 | 1:1000 | Bernard, P.B., et al. 2014. Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizures.. Neuropharmacology, 1-12. |
| 23486974 | not listed | Murata, Y., et al. 2013. Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.. Journal of Neuroscience, 5040-5052. |
| 21209193 | not listed | Chen, B.S., et al. 2011. NMDA receptor-dependent regulation of dendritic spine morphology by SAP102 splice variants.. Journal of Neuroscience, 89-96. |
| 17670980 | not listed | Al-Hallaq, R.A., et al. 2007. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus.. Journal of Neuroscience, 8334-8343. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 21946113 | Gardoni, F., et al. 2011. Effect of rasagiline on the molecular composition of the excitatory postsynaptic density.. European Journal of Pharmacology, 458-463. | |
| 21525273 | Chen, X., et al. 2011. PSD-95 is required to sustain the molecular organization of the postsynaptic density. Journal of Neuroscience, 6329-6338. | |