Anti-Rem2 Antibody (N324/2)

Name: Anti-Rem2 Antibody
Brand: NeuroMab
SKU: 75-286
Price: 319.0 USD
Availability: InStock

Our Anti-Rem2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N324/2. It detects mouse and rat Rem2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Transfected cell immunoblot: extracts of COS cells transiently transfected with HA-tagged Rem2, Rem, Flag-tagged Rad or untagged Gem or Kv2.1 plasmid and probed with N324/2 (left) or 12CA5 (right) TC supe.

Adult rat brain immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Species Reactivity

Mouse, Zebrafish

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-286

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Rem2

Target Description

Rad And Gem-Like GTP-Binding Protein 2 or GTP-binding protein REM 2 is encoded by the gene Rem2 and is a member of the small GTPase superfamily and the Rad/Rem/Rem2/Gem/Kir (RGK) subfamily. REM2 binds GTP and plays roles in diverse processes including modulation of calcium channel currents, (Ref Zheng JQ et al. 2007), mediation of excitatory and inhibitory synapse development (Ref: Paradis et al. 2007). REM2 is expressed in brain and kidney. Diseases associated with this gene include Long Qt Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N324/2

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Rem2

Molecular Weight

45 kDa (and larger due to oligomerization)

Antigen

Fusion protein amino acids 1-341 (full-length) of rat Rem2 (accession number Q9WTY2)

Species Reactivity

Mouse, Zebrafish

Antibody Registry ID

AB_11001585

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Rad, Gem or Rem1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)

UniProt Details

UniProt (Human): Q8IYK8
UniProt (Immunogen Species): Q9WTY2

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Anti-Rem2 Antibody (N324/2)

SKU: 75-286

Product Details

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