Anti-Noggin Antibody

Name: Anti-Noggin Antibody
Brand: PhosphoSolutions
SKU: 36875
Price: 430.0 USD
Availability: InStock

Our Noggin rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human, mouse, and rat Noggin and is antigen affinity purified. It is great for use in WB.

Western Blot of 20 ug of human hippocampus lysate (lanes 2 and 4) showing specific immunolabeling of Noggin and peptide absorption control in lane 3.

Species Reactivity

Human, Mouse, Rat

Applications

Host Species

Rabbit

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SKU: 36875

Title: 100 µL

Variant

Price:

$430.00

Quantity:

Product Details

Target

Noggin

Target Description

Noggin is involved in numerous developmental processes, such as neural tube fusion and joint formation. The morphogenesis of organs is initiated by a downgrowth from a layer of epithelial stem cells. This process is achieved through the receipt of signals from 1) a WNT protein (WNT3A) to stabilize beta-catenin; and 2) Noggin, which is a bone morphogenetic protein inhibitor. Noggin mutations in unrelated families with proximal symphalangism (SYM1) and multiple synostoses syndrome (SYNS1) have been identified, which have multiple joint fusion as their principal defect.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

NOG

Antigen

Synthetic peptide corresponding to amino acids from an internal sequence of the human Noggin protein.

Species Reactivity

Human, Mouse, Rat

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

This antibody reacts with an internal sequence of the human Noggin protein. Sequence is 100% conserved in rat and mouse.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

NOG

UniProt Details

UniProt (Human): Q13253
UniProt (Immunogen Species): Q13253

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Anti-Noggin Antibody

SKU: 36875

Product Details

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