Anti-Adenovirus 3 Antibody

Name: Anti-Adenovirus 3 Antibody
Brand: PhosphoSolutions
SKU: 24110
Price: 430.0 USD
Availability: InStock

Our Adenovirus 3 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human Adenovirus 3 and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human

Applications

Host Species

Rabbit

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SKU: 24110

Title: 100 µL

Variant

Price:

$430.00

Quantity:

Product Details

Target

Adenovirus 3

Target Description

Adenoviruses are DNA viruses generally widespread in nature that are frequently the cause of acute upper respiratory tract infections (i.e. common colds). Forty-seven known serotypes have been isolated since they were first discovered in 1953 with 3 types known to cause gastroenteritis. Several types have oncogenic potential though most cause self-limiting febrile illnesses characterised by inflammation of conjunctivae and the respiratory tract. The virus can be isolated from the majority of tonsils/adenoids surgically removed, indicating latent infections. It is not known how long the virus can persist in the body, or whether it is capable of reactivation after long periods. In patients experiencing immunosuppression (e.g. AIDS) it can be reactivated causing disease. The adenovirus early gene products E1A is a potent stimulator of cellular proliferation, which when overexpressed can overcome the growth inhibitory effects of TGF beta. The E1A region encodes a series of related proteins (35 - 46 kD) with multifunctional capabilities and forms a specific complex with the retinoblastoma tumor suppressor gene product. The E1a and E1B regions together comprise the transforming region of adenovirus. While expression of E1A alone is sufficient to immortalize primary cells, complete transformation requires the additional expression of the E1B region.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Antigen

Synthetic peptide corresponding to amino acids from the fiber knob protein of human Ad 3.

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with an antigenic epitope of the fiber knob of Ad Serotype 3. The fiber knob is involved in the initial interaction of adenovirus with cellular membrane receptors.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

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Anti-Adenovirus 3 Antibody

SKU: 24110

Product Details

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