Our DDP10 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human DDP10 and is antigen affinity purified. It is great for use in WB.
Western Blot of Flag-DPP10 in transfected CHO cells showing specific immunolabeling of DPP10. The expected MW is 75 kDa; however, oligermization and differential glycosylation produces other bands as observed with other DPP family members.
A novel gene, DPP10, encodes a homolog of dipeptidyl peptidases (DPPs) that cleave terminal dipeptides from cytokines and chemokines, and it presents a potential new target for asthma therapy. The DPP10 protein shares features with members of the S9B family of DPP serine proteases, which includes DPP4, a widely expressed enzyme that plays a central role in chemokine processing as part of the innate immune system. The locus displays a complex pattern of transcript splicing, with eight alternate first exons; four of which localize within the LD block strongly associated with asthma.
Antigen Affinity Purified
Polyclonal
IgG
WB
Rabbit
DPP10
Synthetic peptide corresponding to amino acids from an internal region of human DPP10 protein
Human
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Liquid
PBS + 0.02% NaN3
WB: 1:500-1:1000
WB Brain: 1:500-1:1000
Reacts with an internal region of human DPP10.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
United States
After date of receipt, stable for at least 1 year at -20°C.
