Anti-Parvalbumin (L114/81) Recombinant Chicken Chimeric mAb (L114/81)
Our chicken Anti-Parvalbumin recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone L114/81. It detects mouse and rat Parvalbumin, and is purified by affinity chromatography. It is great for use in AT, ICC, IHC, WB.
SKU: 78-479
Product Details
Parvalbumin
Parvalbumin (PA) is a classical small, mostly cytosolic Ca2+-binding protein of the EF-hand superfamily expressed in vertebrates in a tissue- and cell-specific manner, serving as a magnesium/ calcium buffer (Permyakov EA et al., 2017). Parvalbumin (PV)-expressing interneurons are a class of inhibitory neurons that fire rapid barrages of action potentials, and are accordingly named “fast-spiking” interneurons (Trachtenberg J. 2015).
Purified by affinity chromatography
1 mg/mL
Recombinant
L114/81
IgY
AT, ELISA, ICC, IHC, WB
Chicken
Pvalb Pva
20 kDa
Fusion protein amino acids 1-110 (full-length) of rat Parvalbumin (accession number P02625) produced recombinantly in E. Coli
Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of our NeuroMab clone L114/81 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone L114/81 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media.
1X PBS, 0.05% Sodium Azide pH 7.4
Unconjugated
No cross-reactivity reported
Each new lot of antibody is quality control tested by Western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Parvalbumin alpha
UniProt (Human): Q9H598