Anti-Dicer Antibody FL550 Conjugate (N167/7)

Name: Anti-Dicer Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-196-FL550
Price: 460.0 USD
Availability: InStock

Our Anti-Dicer mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N167/7. It is KO validated, detects human, mouse, and rat Dicer, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

594

650

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Data Sheet

KO Validated

SKU: 75-196-FL550

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Dicer

Target Description

Endoribonuclease Dicer or Dicer 1, Ribonuclease III is encoded by the gene DICER1. DICER1 acts as a double stranded (ds) ribonuclease and plays a role in short post transcriptional gene silencing. DICER1 cleaves full length dsRNA and miRNA into smaller moleclues 21-23 nucleotides in length, called siRNAs and microRNAs. Dicer1 is expressed in a variety of tissues, including brain. Diseases associated with this gene include Pleuropulmonary Blastoma, Glow Syndrome and Wilms Tumor.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N167/7

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Dicer1 Dicer Mdcr

Molecular Weight

215 kDa

Antigen

Fusion protein amino acids 1638-1899 of mouse Endoribonuclease Dicer (accession number Q8R418) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939725

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Endoribonuclease Dicer (EC 3.1.26.3) (Double-strand-specific ribonuclease mDCR-1)

UniProt Details

UniProt (Human): Q9UPY3
UniProt (Immunogen Species): Q8R418

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Anti-Dicer Antibody FL550 Conjugate (N167/7)

SKU: 75-196-FL550

Product Details

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