Our Anti-SNAT1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N104/37. It detects human, mouse, and rat SNAT1, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Sodium-coupled neutral amino acid transporter 1 (SNAT1) or Solute Carrier Family 38 Member 1 is encoded by the gene Slc38a1 and belongs to the amino acid/polyamine transporter 2 family. SNAT1 acts as a sodium-dependent transporter of glutamine which serves as a precursor for the synaptic transmitter, glutamate. SNAT1 is expressed in brain, specifically at glutamatergic and GABAergic neurons, and also expressed in placenta, heart, lung, skeletal muscle, spleen, stomach and testis. Diseases associated with this gene include Klatskin's Tumor.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N104/37
IgG1
ICC, WB
Mouse
Slc38a1 Ata1 Glnt Sa2 Sat1 Snat1
50 kDa
Fusion protein amino acids 1-63 (cytoplasmic N-terminus) of rat SNAT1 (accession number Q9JM15) produced recombinantly in E. Coli
Human, Mouse, Rat
AB_2254872
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.81
Unconjugated
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Sodium-coupled neutral amino acid transporter 1 (Amino acid transporter A1) (rATA1) (Glutamine transporter) (N-system amino acid transporter 2) (Solute carrier family 38 member 1) (System A amino acid transporter 1) (System A transporter 2) (System N amino acid transporter 1)
Brown, M.N., et al. 2010. Activity- and age-dependent modulation of GABAergic neurotransmission by system A-mediated glutamine uptake.. Journal of Neurochemistry, 909-920.
Gauthier-Coles, G., et al. 2022. Identification and Characterization of a Novel SNAT2 (SLC38A2) Inhibitor Reveals Synergy with Glucose Transport Inhibition in Cancer Cells. Frontiers in Pharmacology, 963066.
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