Anti-Kirrel3 Short Isoform 3 Antibody (N320/48)

Name: Anti-Kirrel3 Short Isoform 3 Antibody
Brand: NeuroMab
SKU: 75-282
Price: 319.0 USD
Availability: InStock

Our Anti-Kirrel3 short isoform 3 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N320/48. It detects mouse Kirrel3 short isoform 3, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Transfected cell immunoblot: extracts of COS cells transiently transfected with Flag-tagged Kirrel3-short, Kirrel3-long or untagged Kv2.1 plasmids and probed with N320/48 (left) and Mouse anti-Flag (right).

Adult rat hippocampus immunohistochemistry (with antigen retrieval via sodium citrate pretreatment).

Species Reactivity

Mouse

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-282

Product Details

Target

Kirrel3 short isoform 3

Target Description

Kirre Like Nephrin Family Adhesion Molecule 3 is encoded by the gene KIRREL3. KIRREL3 is a member of the immunoglobulin superfamily, nephrin-like protein family. KIRREL3 is a synaptic cell adhesion molecule with multiple extracellular immunoglobulin-like domains and a cytoplasmic PDZ domain-binding motif. KIRREL3 is expressed in brain, bone marrow, and stromal cells. Diseases associated with KIRREL3 include Autosomal Dominant Non-Syndromic Intellectual Disability and Autosomal Dominant Non-Syndromic Intellectual Disability 4.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N320/48

Isotype

IgG2a

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Kirrel3 Kiaa1867 Neph2

Molecular Weight

70 kDa

Antigen

Synthetic peptide amino acids 591-608 (VRAQPMPHSILSTQTSRC) of mouse Kirrel3 short isoform 3 (accession number Q8BR86-3)

Species Reactivity

Mouse

Antibody Registry ID

AB_2341106

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with other Kirrel3 isoforms

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Kin of IRRE-like protein 3 (Kin of irregular chiasm-like protein 3) (Nephrin-like protein 2) (mKirre) [Cleaved into: Processed kin of IRRE-like protein 3]

UniProt Details

UniProt (Human): Q8IZU9
UniProt (Immunogen Species): Q8BR86-3

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Anti-Kirrel3 Short Isoform 3 Antibody (N320/48)

SKU: 75-282

Product Details

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