Anti-Pan-Gamma-Protocadherin-Constant Antibody (N159/5)
Our Anti-Pan-Gamma-protocadherin-Constant mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N159/5. It is KO validated, detects mouse Pan-Gamma-protocadherin-Constant, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Immunostaining of spinal cord samples from WT and Gamma-protocadherin KO mice with N159/5 TC supe. Data courtesy of Joshua Weiner, University of Iowa.
Product Specific References for Applications and Species
- Immunocytochemistry: Human | Rat
- Immunohistochemistry: Mouse | Non-Human Primate | Rat
- Western Blot: Mouse | Rat
- Additional Publications: Unspecified
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 21917590 | not listed | O'Leary, R., et al. 2011. A variable cytoplasmic domain segment is necessary for γ-protocadherin trafficking and tubulation in the endosome/lysosome pathway.. Molecular Biology of the Cell, 4362-4372. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 31609469 | 1:15 | Miralles, C.P., et al. 2020. Expression of protocadherin-γC4 protein in the rat brain. Journal of Comparative Neurology, 840-864. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 38837880 | 1:500 | Hanes, C.M., et al. 2024. A C-terminal motif containing a PKC phosphorylation site regulates γ-Protocadherin-mediated dendrite arborization in the cerebral cortex in vivo. Developmental Neurobiology, 217-235. |
| 30208308 | 1:200 | Kuwako, K.I., et al. 2018. The LKB1-SIK Pathway Controls Dendrite Self-Avoidance in Purkinje Cells. Cell Reports, 2808-2818. |
| 25352748 | 1:400 | de Andrade, G.B., et al. 2014. Developmentally dynamic colocalization patterns of DSCAM with adhesion and synaptic proteins in the mouse retina.. Molecular Vision, 1422-33. |
| 25176525 | 1:400 | Nuhn, J.S., et al. 2014. Developmental localization of adhesion and scaffolding proteins at the cone synapse. Gene expression patterns, 36-50. |
| 22275881 | not listed | Prasad, T., et al. 2011. Direct and Indirect Regulation of Spinal Cord Ia Afferent Terminal Formation by the γ-Protocadherins.. Frontiers in Molecular Neuroscience, 54. |
| Immunohistochemistry: Non-Human Primate | ||
| PMID | Dilution | Publication |
| 25176525 | 1:400 | Nuhn, J.S., et al. 2014. Developmental localization of adhesion and scaffolding proteins at the cone synapse. Gene expression patterns, 36-50. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 20849527 | not listed | Fernández-Monreal, M., et al. 2010. γ-protocadherins are enriched and transported in specialized vesicles associated with the secretory pathway in neurons.. European Journal of Neuroscience, 921-931. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 31877124 | 1:500-1:1000 | Garrett, A.M., et al. 2019. CRISPR/Cas9 interrogation of the mouse Pcdhg gene cluster reveals a crucial isoform-specific role for Pcdhgc4. . PLoS genetics, e1008554. |
| 26139604 | not listed | Keeler, A.B., et al. 2015. Protein Kinase C Phosphorylation of a γ-Protocadherin C-terminal Lipid Binding Domain Regulates Focal Adhesion Kinase Inhibition and Dendrite Arborization.. The Journal of Biological Chemistry, 20674-20686. |
| 22884324 | not listed | Chen, W.V., et al. 2012. Functional significance of isoform diversification in the protocadherin gamma gene cluster.. Neuron, 402-409. |
| 22542181 | not listed | Garrett, A.M., et al. 2012. γ-protocadherins control cortical dendrite arborization by regulating the activity of a FAK/PKC/MARCKS signaling pathway.. Neuron, 269-276. |
| 22092001 | not listed | Lobas, M.A., et al. 2012. Molecular heterogeneity in the choroid plexus epithelium: the 22-member γ-protocadherin family is differentially expressed, apically localized, and implicated in CSF regulation. Journal of Neurochemistry, 913-927. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 20589908 | 1:15 | Li, Y., et al. 2010. Synaptic and nonsynaptic localization of protocadherin-gammaC5 in the rat brain. Journal of Comparative Neurology, 3439-3463. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 33381867 | LaMassa, N., et al. 2020. Gamma-protocadherin localization at the synapse is associated with parameters of synaptic maturation. Journal of Comparative Neurology, 2407-2417. | |