Anti-TRIP8b (Exon 4) Antibody (N212/3)
Our Anti-TRIP8b (exon 4) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N212/3. It is KO validated, detects human, mouse, and rat TRIP8b (exon 4), and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Transfected cell immunoblot: extracts of COS cells transiently transfected with GFP-tagged TRIP8b-1a-4, TRIP8b-1b-2, TRIP8b-1a-2 or untagged Kv2.1 plasmid and probed with N212/3 (left) and N86/8 (right) TC supe.
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Human, Mouse, Rat
ICC, IHC, WB
Mouse
KO Validated
Product Specific References for Applications and Species
- Immunohistochemistry: Mouse
- Western Blot: Mouse | Rat
- Additional Publications: Unspecified
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 32467357 | 1:1000 | Brandalise, F., et al. 2020. Fragile X Mental Retardation Protein Bidirectionally Controls Dendritic Ih in a Cell Type-Specific Manner between Mouse Hippocampus and Prefrontal Cortex. Journal of Neuroscience, 5327-5340. |
| 24409334 | 1:1000 | Pan, Y., et al. 2014. TRIP8b is required for maximal expression of HCN1 in the mouse retina.. PLoS One, e85850. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 33547341 | 1:1000 | Rátkai, A., et al. 2021. Homeostatic plasticity and burst activity are mediated by hyperpolarization-activated cation currents and T-type calcium channels in neuronal cultures. Scientific Reports, 3236. |
| 31492750 | 1:1500 | Foote, K.M., et al. 2019. Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function. Journal of Biological Chemistry, 15743-15758. |
| 29662202 | not listed | Yun, S., et al. 2018. Stimulation of entorhinal cortex-dentate gyrus circuitry is antidepressive. Nature Medicine, 658-666. |
| 21555075 | not listed | Piskorowski, R., et al. 2011. TRIP8b splice forms act in concert to regulate the localization and expression of HCN1 channels in CA1 pyramidal neurons.. Neuron, 495-509. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 36018183 | 1:500 | Luo, X.D., et al. 2023. Activation of Metabotropic Glutamate Receptor 1 Regulates Hippocampal CA1 Region Excitability in Rats with Status Epilepticus by Suppressing the HCN1 Channel. Neural Regeneration Research, 594-602. |
| 31492750 | 1:1500 | Foote, K.M., et al. 2019. Phosphorylation of the HCN channel auxiliary subunit TRIP8b is altered in an animal model of temporal lobe epilepsy and modulates channel function. Journal of Biological Chemistry, 15743-15758. |
| 29650696 | 1:10,000 | Villarroel, H.S., et al. 2018. NPY Induces Stress Resilience via Downregulation of Ih in Principal Neurons of Rat Basolateral Amygdala. Journal of Neuroscience, 4505-4520. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 25301101 | Zhou, M., et al. 2015. Imbalance of HCN1 and HCN2 expression in hippocampal CA1 area impairs spatial learning and memory in rats with chronic morphine exposure.. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 207-214. | |
| 24838625 | Li, C.J., et al. 2014. Activation of GABAB receptors ameliorates cognitive impairment via restoring the balance of HCN1/HCN2 surface expression in the hippocampal CA1 area in rats with chronic cerebral hypoperfusion.. Molecular Neurobiology, 704-720. | |